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KMID : 0984920170190020005
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Journal of Skin Barrier Research
2017 Volume.19 No. 2 p.5 ~ p.9
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Alteration of Stratum Corneum pH in Aged Skin and Its Clinical Significance
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Man Mao-Qiang
Peter M. Elias
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Abstract
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In comparison with young skin, aged epidermis displays multiple functional abnormalities, including elevated stratum corneum pH and compromised permeability barrier homeostasis. In this article, we briefly review the alteration of stratum corneum pH, its underlying mechanisms, as well as the clinical significance of elevated stratum corneum pH in the aged population. We also brief the rapidly expanding and clinical implications of SC acidification.
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KEYWORD
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Aging, Barrier function, pH, Stratum corneum
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